A product of alpha-fetoprotein and protein induced by vitamin K absence-II is a powerful predictor of prognosis and recurrence in hepatocellular carcinoma patients after a hepatectomy

A product of alpha-fetoprotein and protein induced by vitamin K absence-II is a powerful predictor of prognosis and recurrence in hepatocellular carcinoma patients after a hepatectomy - AP-factorHCC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000017448

Enrollment

516

Registered

2015-05-11

Start date

2013-05-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Between January 1998 and December 2010, 516 consecutive adult patients underwent a hepatectomy for HCC at our center.

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: hepatectomized patients

Exclusion criteria

Exclusion criteria: without hepatectomy

Design outcomes

Primary

Measure	Time frame
AP-factor (AFP X PIVKA-II) was evaluated in relation to 2-year survival outcomes by receiver operating characteristics (ROC) analysis to determine the cut-off values. Patient survival, recurrence-free survival and risk factors were analyzed in accordance with the preoperative AP-factor.	—

Countries

Japan

Contacts

Public ContactToshiya Kamiyama

Hokkaido University Gastroenterological Surgery I

t-kamiya@med.hokudai.ac.jp+81117065927

Outcome results