Mild cognitive impairment (MCI) Healthy adult volunteers
Conditions
Interventions
None listed
Sponsors
Department of Neurology Oita University Faculty of Medicine
TOSHIBA TDK
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: <Inclusion criteria of MCI> (1)Subject who lives in Usuki city. (2)Willing and able to complete the protocol. (3)MCI who fulfilled the diagnostic criteria of Petersen (CDR 0.5). <Inclusion criteria of healthy adult volunteers> (1)Subject who lives in Usuki city. (2)Willing and able to complete the protocol. (3)Healthy adult volunteers who did not fulfill the diagnostic criteria of Petersen (CDR 0).
Exclusion criteria
Exclusion criteria: Any significant neurologic or psychiatric disease other than MCI (1). History of significant head trauma, alcohol or substance abuse (2,6,7). Any significant systemic illness or unstable medical condition which could lead to difficulty complying with the protocol : diabetes mellitus, thyroid disease, anemia, cardiac disease, or hypertension (3,4,5,10,11). Clinically significant and severe abnormalities in hepatic and/or renal function (8,9). Subjects who participate in another study within 3 months (12). Subjects who donated blood (over 200ml or over 400ml, within 1 month or 3 months, respectively (13). Subjects who are judged to be inadequate for their eligibility by investigators (14).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of non-genetic risk factors for onset of AD via analysis of differences between MCI individuals that convert to AD and MCI nonconverters (who have been scanned using PET) | — |
Secondary
| Measure | Time frame |
|---|---|
| Group differences for each imaging and biomarker measurement. | — |
Countries
Japan
Contacts
Public ContactNoriyuki Kimura
Oita University Faculty of Medicine Department of Neurology
Outcome results
None listed