Chronic inflammatory airway diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: # Those who were diagnosed as having chronic pulmonary diseases including COPD, chronic bronchitis, bronchiectasis, old tuberculosis, etc, who are suffering from chronic productive cough. # Those who have 5 times or more of sputum a day which takes more than 30 seconds to be expectorated. # No change of medication 4 weeks prior to the entry to the study.
Exclusion criteria
Exclusion criteria: # Systemic corticosteroi use 4 weeks prior to the entry to the study. # Respiratory tract infection 4 weeks prior to the entry to the study. # Co-existence of GERD, neuromuscular diseases, active airway bleeding, uncontrolled asthma, recent pneumothorax. # Operation of thorax or abdomen 4 weeks prior to the entry to the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The degree of improvement of difficulties in expectoration sputum. | — |
Secondary
| Measure | Time frame |
|---|---|
| QOL, Pulmonary function tests | — |
Countries
Japan
Contacts
National Hospital Organization Disaster Medical Center Pulmonology Department