Combined Use of 18F-FDG PET and Corticosteroid for Diagnosis of Deep-seated Primary Central Nervous System Lymphoma without Histopathological Confirmation

Combined Use of 18F-FDG PET and Corticosteroid for Diagnosis of Deep-seated Primary Central Nervous System Lymphoma without Histopathological Confirmation - PCNSL diagnosis based on FDG PET and corticosteroid

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000017401

Enrollment

Registered

2015-05-02

Start date

2013-08-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Central Nervous System Lymphoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) there was no evidence of systemic malignancy (2) the tumor was located in the deep site of brain, such as in the hypothalamus, brainstem including cerebral peduncle, and cerebellar peduncle, or periventricular infiltration (3) the tumor had a high FDG uptake on PET, which is defined as when the FDG uptake of lesion is relatively higher than the that of adjacent and contralateral gray matter based on the visual inspection (4) patients were radiological responders to corticosteroid administration

Exclusion criteria

Exclusion criteria: any cases which were not matched every inclusion criteria

Design outcomes

Primary

Measure	Time frame
Diagnostic accuracy	—

Countries

Japan

Contacts

Public ContactShigeru Yamaguchi

Hokkaido University Department of Neurosurgery

yama-shu@med.hokudai.ac.jp011-706-5987

Outcome results