Unresectable colorectal cancer
Conditions
Interventions
None listed
Sponsors
Gastroenterological Surgery1, Hokkaido University Graduate school of medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The cases histologically diagnosed as colorectal cancer 2. The cases without a history of chemotherapy 3. The cases with evaluative cancer lesions based on RECIST 4. The cases with wild-type about KRAS status 5. The age is 20 years old and older. 6. Performance status is 0-2 cases 7. A major organ function is maintained by a laboratory study. 8. The cases could survive at least for 3 months from the registration day. 9. An agreement is obtained in a document from the patients.
Exclusion criteria
Exclusion criteria: 1. The cases with serious drug hypersensitivity or allergy 2. Multiple primary cancers 3. The cases with symptomatic brain metastasis 4. The cases with infectious disease requiring systemic therapy 5. The cases with serious complications - Interstitial pneumonia, pulmonary fibrosis - Heart failure - Renal failure - Liver failure - Poor control diabetes mellitus - Icterus 6. Pregnant or lactating women 7. The cases judged to be unsuitable for registration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Resection rate, Progression free survival, Overall survival, Safety | — |
Countries
Japan
Contacts
Public ContactNorihiko Takahashi
Hokkaido University Hospital Gastroenterology1
Outcome results
None listed