chronic low back pain
Conditions
Interventions
anti-IL-6 inhibitor 162mg subcutaneous administration
Saline administered subcutaneously
Sponsors
Department of Orthopaedic surgery Graduate school of medicine, Chiba University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -exhibit low back pain, the leg pain. -X-ray, CT, MRI, in the imaging findings such as discography, have the findings that can explain the symptoms. -within between two vertebral disc degeneration. -spinal instability. 5 degrees or more before and after bending X-ray. -agreement to this test. -resistance to conservative treatment.
Exclusion criteria
Exclusion criteria: -consciousness disorders -Heart failure, renal failure, which exhibit liver failure, severe systemic complications such as respiratory failure -cardiac function is severely degraded has a history of myocardial infarction -Unstable angina merged patients cardiac function is severely degraded -severe renal disease (BUN 30 mg / dL or more or serum creatinine 2.0 mg / dL or more) -severe liver disease (AST (GOT) or ALT (GPT) is more than 100 U) -respiratory function is severely degraded have-respiratory history And infectious diseases, interstitial pneumonia, emphysema, malignant tumor Other, if the study at the discretion of respiratory medicine physician it is determined difficult -psychotic or psychiatric symptoms -Potential women during pregnancy pregnant, lactating women -Patients were judged to be inappropriate as-subject
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Low back pain assessment and side effects of anti-IL6 therapy | — |
Countries
Japan
Contacts
Public ContactTakeshi Sainoh
Department of Orthopaedic surgery Department of Orthopaedic surgery
Outcome results
None listed