Oral tolerance for oral allergy syndrome to apple

Oral tolerance for oral allergy syndrome to apple - Oral tolerance for oral allergy syndrome to apple

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017251

Enrollment

Registered

2015-04-23

Start date

2015-04-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral allergy syndrome

Interventions

apple intake 8 month Without treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Nasal allergy Birch-pollen RAST positive Positeve oral provocation test for apple Informed concent

Exclusion criteria

Exclusion criteria: Pregnancy Sever underlying disease Allergy for nuts and fruits Severe asthma Past immune therapy Positive Rast for Prup 3 others

Design outcomes

Primary

Measure	Time frame
The percentage of patients who can eat 128g of apple.	—

Secondary

Measure	Time frame
1.oral symptom for other meals 2.nasal symptom for birch pollen 3.changes of laboratory findings	—

Countries

Japan

Contacts

Public ContactNakamaru Yuji

Hokkaido University Hospital otorhinolaryngology

nmaru@med.hokudai.ac.jp011-706-5958

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026