Prospective Phase II Study of Image-guided Local Boost Using a Real-time Tumor-tracking Radiotherapy (RTRT) System for Locally Advanced Bladder Cancer

Prospective Phase II Study of Image-guided Local Boost Using a Real-time Tumor-tracking Radiotherapy (RTRT) System for Locally Advanced Bladder Cancer - RTRT-guided radiotherapy for bladder cancer

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017227

Enrollment

Registered

2015-04-21

Start date

1999-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bladder cancer

Interventions

implantation of fiducial markers for radiotherapy and image guidance using fiducial markers and Real time tumor tracking radiotherapy system

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (i) histologically confirmed urothelial cancer (ii) T2-T4N0M0 with or without hydronephrosis (iii) WHOperformance status 0-2 (iv) clinically inoperable or refused surgery (v) provision of written informed consent.

Exclusion criteria

Exclusion criteria: Patients with tumors that covered all or most of the bladder wall and patients with small cell carcinoma were excluded.

Design outcomes

Primary

Measure	Time frame
5-year overall survival	—

Secondary

Measure	Time frame
treatment related toxicity local control rate	—

Countries

Japan

Contacts

Public ContactShinichi Shimizu

Hokkaido University Graduate School of Medicine Department of Radiation Oncology

sshing@med.hokudai.ac.jp+81-11-706-5977

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026