postoperative pneumonia after esophagectomy for esophageal cancer
Conditions
Interventions
Intravenous administration of Biapenem 300mg every six hours for the patient of postoperative pneumonia after esophagectomy
Sponsors
Department of Gastrointestinal Surgery, The University of Tokyo Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Canditates for esophagectomy in the University of Tokyo Hospital are pre-registered as candidates of this study. No exclusion criteria for the reconstruction methods. Well informed and written convent. Patients with the written informed concent are registered when diagnosed as postoperative pneumonia within 14 days after the operation along with the standard diagnostic criteria.
Exclusion criteria
Exclusion criteria: Other infectious disease including SSI is present. History of hyper reactive events caused by carbapenem. The suspected pathogenic microbes of the pneumonia is; MRSA, MDRP, virus, mycoplasma, regionera, clmamigia, MAC, yeast. MRSA or MDRP is present in any culture specimen during the in hospital course. History of epilepsy or barproic acid use. Renal disease with Ccr lower than 20ml/kg.min or requiring hemodialysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Days required for the treatment of Biapenem Postoperative hospital stay | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical and bacteriological efficacy rates at each time point during the use of Biapanem. | — |
Countries
Japan
Contacts
Public ContactKoichi Yagi
The University of Tokyo Hospital Department of Gastrointestinal Surgery
Outcome results
None listed