Influence of carbon dioxide on dynamic cerebral autoregulation during simulated microgravity

Influence of carbon dioxide on dynamic cerebral autoregulation during simulated microgravity - Influence of carbon dioxide on dynamic cerebral autoregulation during simulated microgravity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017157

Enrollment

Registered

2015-04-17

Start date

2014-03-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult volunteers. e.g. astronauts, or exposure to carbon dioxide during head down tilt, etc.

Interventions

exposure to CO2 (-), head-down tilt (-) exposure to CO2 (+), head-down tilt (-) exposure to CO2 (-), head-down tilt (+) exposure to CO2 (+),head-down tilt (+)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adult consented to participate in this study.

Exclusion criteria

Exclusion criteria: Not satisfy selection criteria noted above

Design outcomes

Primary

Measure	Time frame
Gain, coherence and phase between arterial blood pressure and cerebral blood flow velocity during 10-min exposure to CO2 with head-down tilt	—

Secondary

Measure	Time frame
cerebral blood flow velocity, pulsatility index, blood pressure variability, cerebral blood flow velocity variability, respiratory indexes, intracranial pressure, NIRS, baroreflex function, HRV	—

Countries

Japan

Contacts

Public ContactKenichi Iwasaki

Nihon University School of Medicine Division of Hygiene, Department of Social Medicine

iwasaki.kenichi@nihon-u.ac.jp03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026