Personalized therapy for methotrexate in patients with rheumatoid arthritis

Personalized therapy for methotrexate in patients with rheumatoid arthritis - Personalized therapy for methotrexate

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000017104

Enrollment

300

Registered

2015-04-11

Start date

2015-04-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthiritis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Among patient who get outpatient treatment in the University Hospital and have the prescription history of methotrexate, and/or will newly start to prescribe methotrexate, all patients who we could get informed consent for this study are target population

Exclusion criteria

Exclusion criteria: Nothing special defined

Design outcomes

Primary

Measure	Time frame
Clinical effectiveness such as DAS28, etc.	—

Secondary

Measure	Time frame
genotype frequencies of enzyme and transporter related to methotrexate, the concentration of methotrexate polyglutamates (MTX-PGs), frequencies of DNA methylation	—

Countries

Japan

Contacts

Public ContactMasayuki Hashiguchi

Keio Univeristy Faculty of Pharmacy

hashiguchi-ms@pha.keio.ac.jp03-5400-2120

Outcome results