breast cancer
Conditions
Interventions
accelerated partial breast irradiation using external beam radiotherapy after breast-conserving surgery
Sponsors
Department of Radiation Therapeutics and Oncology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Clinically tumor diameter is less than or equal to 2 cm. 3) Clinically negative nodes and negative metastases. 3) Negative multicentric disease. 4) Histologically ductal carcinoma. 5) After breast-conserving surgery and insertion of surgical clips in tumor resection margin. 6) Histologically no tumor cells within 5 mm from the surgical margin 7) Negative axillary nodes and/or negative sentinel nodes. 8) Written informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with operation other than lumpectomy. 2) Patients with non-epithelial breast malignancies such as sarcoma or lymphoma. 3) Patients with proven multicentric disease. 4) Time between final definitive breast procedure to beginning radiotherapy is greater than 8 weeks. 5) Prior non-hormonal therapy for the present breast cancer. 6) Prior ipsilateral breast or thoracic radiotherapy. 7) Patients who are pregnant or lactating. 8) Patients with collagen vascular disease. 9) Patietns with psychiartic or addictive disorders. 10) Other malignancy. 11) Patients with uncontrolled diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rate of completion of protocol treatment | — |
Countries
Japan
Contacts
Public ContactRyoichi Yoshimura
Graduate School of Medical and Dental Sciences,Tokyo Medical and Dental University Department of Radiation Therapeutics and Oncology
Outcome results
None listed