The study to prevent and reduce postoperative nausea and vomiting due to continuous epidural administration

The study to prevent and reduce postoperative nausea and vomiting due to continuous epidural administration - The effectiveness of epidural droperidol for prophylaxis of postoperative nausea and vomiting: a comparative study of droperidol and adrenaline

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017055

Enrollment

Registered

2015-04-06

Start date

2013-11-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients scheduled for abdominal gynecological surgery under general-epidural anesthesia

Interventions

epidural administration of 0.2% ropivacaine 200ml, fentanyl 14ml and droperidol 2ml, 4ml/hr of administration rate, and 3ml of bolus injection, during about 50 hours. epidural administration of 0.2% r

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: patients scheduled for abdominal gynecological surgery under general-epidural anesthesia

Exclusion criteria

Exclusion criteria: age<18, >=80, ASA-PS<=3, BMI<=35, QT prolongation, Parkinson's disease, psychiatric history, drug abuser, steroid administration

Design outcomes

Primary

Measure	Time frame
the incidences of PONV, the use frequency of the antiemetics	—

Secondary

Measure	Time frame
the incidences of cancelling continuous epidural administration for vomiting, the use frequency of the adjuvant analgesic, the incidences of pruritus, the incidences of reduction in blood pressure	—

Countries

Japan

Contacts

Public ContactShinya Toyonaga

Saiseikai Narashino Hospital Department of Aneasthesia

redhunter-2005-@hotmail.co.jp047-473-1281

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026