Randomized study of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) versus transesophageal endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for histological diagnosis of sarcoidosis

Randomized study of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) versus transesophageal endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for histological diagnosis of sarcoidosis - Comparison of EBUS-TBNA versus EUS-FNA for diagnosing sarcoidosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017040

Enrollment

160

Registered

2015-04-05

Start date

2015-04-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcoidosis

Interventions

EBUS-TBNA EUS-FNA

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with suspected stage I/II sarcoidosis based on clinicoradiological pictures who have hilar-mediastinal nodes 10 mm or greater in short-axis diameter on CT 2. 20 years or older 3. Informed consent

Exclusion criteria

Exclusion criteria: 1. Serious concomitant medical illness 2. SPO2<90% with supplemental oxygen 3. Obvious bleeding tendency 4. Pregnancy 5. Other presumed difficulties for patients in this study

Design outcomes

Primary

Measure	Time frame
1. Sensitivity for histological diagnosis of sarcoidosis	—

Secondary

Measure	Time frame
1. Sensitivity for cytological diagnosis of sarcoidosis 2. Overall sensitivity for the diagnosis of sarcoidosis (cytology and histology) 3. Overall diagnostic yield 4. Tolerance assessed by visual analog scale (discomfort, anxiety, satisfaction, coughing, vomiting, pain, dyspnea, willing to repeat procedure) 5. Time of procedure 6. Frequency of complications 7. Oxygen demand 8. Doses of sedative and anesthetic 9. Number of evaluable lymph nodes	—

Measure

Time frame

1. Sensitivity for cytological diagnosis of sarcoidosis 2. Overall sensitivity for the diagnosis of sarcoidosis (cytology and histology) 3. Overall diagnostic yield 4. Tolerance assessed by visual analog scale (discomfort, anxiety, satisfaction, coughing, vomiting, pain, dyspnea, willing to repeat procedure) 5. Time of procedure 6. Frequency of complications 7. Oxygen demand 8. Doses of sedative and anesthetic 9. Number of evaluable lymph nodes

—

Countries

Japan

Contacts

Public ContactMasahide Oki

Nagoya Medical Center Department of Respiratory Medicine

masahideo@gmail.com052-951-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026