Effect of advance of age on the minimum alveolar concentrations of desflurane for maintaining bispectral index below 50

Effect of advance of age on the minimum alveolar concentrations of desflurane for maintaining bispectral index below 50 - Effect of advance of age on the adequate level of anesthesia with desflurane

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016994

Enrollment

Registered

2015-03-31

Start date

2015-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases requiring surgical treatment

Interventions

To provide general anesthesia with predetermined concentration of desflurane to young (20-30 yr)patients and measure bispectral index To provide general anesthesia with predetermined concentration of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with American Society of Anesthesiologysts physical status I or II

Exclusion criteria

Exclusion criteria: Patients with 1) asthma, 2) arrhythmia, 3) psychiatric diseases or neuromuscular diseases 4) ischemic heart diseases or decreased cardiac function with left ventricular ejection fraction equal to or lower than 40% 5) hypotension with systolic blood pressure equal to or lower than 80 mmHg 6) Serum sodium levels equal to or lower than 135 mEq/l or equal to or higher than 148 mEq/l

Design outcomes

Primary

Measure	Time frame
Bispectral index during anesthesia with desflurane	—

Countries

Japan

Contacts

Public ContactYutaka Oda

Osaka City General Hospital and Children's Hospital Department of Anesthesiology

odayou@s5.dion.ne.jp81-6-6929-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026