pancreatic cancer
Conditions
Interventions
None listed
Sponsors
Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital
Shonan Kamakura General Hospital Chiba Tokushukai Hospital Teine Keijinkai Hospital Shibetsu City Hospital Chiba-Nishi General Hospital Uji Tokushukai Medical Center Massachusetts General Hospital Asahikawa Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: For saliva and blood collection: Patients and volunteers who have given written informed consent Pancreatic cancer group: 1.Age between 20 and 49 2.Cases with histologically confirmed pancreatic ductal adenocarcinoma Control group: 1.Age older than 80 2.Healthy volunteers who have no the medical history of cancers and pre-malignant neoplasms. For tumor tissue collection: 1.Age older than 20 2.Cases with histologically confirmed pancreatic ductal adenocarcinoma 3.Available surgically resected tissue (formalin fixed paraffin embedded block) from pancreatic cancer
Exclusion criteria
Exclusion criteria: Cases with neuroendocrine tumor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whole-exome sequencing using genomic DNA isolated from saliva, blood and the tissue | — |
Secondary
| Measure | Time frame |
|---|---|
| Histopathological analysis and somatic mutation, gene expression and methylation analysis using the resected specimens | — |
Countries
Japan,North America
Contacts
Public ContactYusuke Mizukami
Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital Division of Cancer Research
Outcome results
None listed