Efficacy of consensus guideline on nutritional management and swallowing training for acute and subacute stroke patients

Efficacy of consensus guideline on nutritional management and swallowing training for acute and subacute stroke patients - APPLE Study

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016896

Enrollment

125

Registered

2015-04-30

Start date

2015-06-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute stroke

Interventions

Oral care Indirect methods Repetitive saliva swallowing test , RSST Modified water swallow test, MWST Food test, FT Direct training

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. NIHSS on admission: from 10 to 30 2. mRS before stroke: from 0 to 1 3. Patients orally can take food without water intake before stroke.

Exclusion criteria

Exclusion criteria: 1. Both supra-tentorial and infral-tentorial lesions. 2. Definite subarachnoid hemorrhage 3. Digestive tract function reducing due to inflammatory bowel disease or short bowel syndrome. 4. Oral intake is difficult due to dysphagia, drug-induced organic disorder, or dementia before stroke. 5. Inappropriate by physician.

Design outcomes

Primary

Measure	Time frame
Body Mass Index, BMI	—

Secondary

Measure	Time frame
Oral intake level Albumin Functional Independence Measure, FIM	—

Countries

Japan

Contacts

Public ContactKuniaki Ogasawara

Iwate Medical University Department of Neurosurgery

kuogasa@iwate-med.ac.jp019-651-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026