Exploratory Research for the induction of natural killer cell propagated from G-CSF mobilized hematopoietic stem cells that were collected by apheresis method

Exploratory Research for the induction of natural killer cell propagated from G-CSF mobilized hematopoietic stem cells that were collected by apheresis method - Exploratory Research for the induction of NK cell propagated from hematopoietic stem cells in peripheral blood

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016851

Enrollment

Registered

2015-03-20

Start date

2015-03-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hapatocellular carcinoma

Interventions

G-CSF and apheresis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (a) Healthy volunteer who agreed the purpose of this research (b) more than 20 years old or less than 70years old (c) The person who can come to this hospital continuously as per the time interval mentioned in the protocol (d) Informed consent must be taken.

Exclusion criteria

Exclusion criteria: (a) The person who suffered allergic reaction from the material of GRAN or other G-CSF (b) The level of blood test as mentioned below. Hgb: less than 12 (female), or 13 (male) WBC: less than 3000 /mm^3 Neutrophil:less than 1500 /mm^3 Platelet: less than 100 x 10^3 /mm^3 Biochemical test as mentioned below. AST, ALT, T-Bil, ALP, g-GTP, LDH, Total protein, Alb, T-chol, BUN, Cr, Na, K, Cl, Uric acid and CRP: more than standard level (c) The people who can stop drinking during injection of G-CSF (d) The breast feeding mother or pregnantlady (e) The doctor's disagrement for the registration due to some underlying medical conditon

Design outcomes

Primary

Measure	Time frame
The number of NK cell from hematopoietic stem cell	—

Countries

Japan

Contacts

Public ContactYuka Tanaka

Hirohshima university Department of Gastroenterological and Transplant Surgery

yukasan@hiroshima-u.ac.jp082-257-5222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026