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Gene expression of renin-angiotensin-system components in human leukocytes study

Gene expression of renin-angiotensin-system components in human leukocytes study - Gene expression of renin-angiotensin-system components in human leukocytes study(GIRASOLE study)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000016846
Enrollment
200
Registered
2015-03-19
Start date
2015-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with chronic kidney disease, hypertension, diabetes mellitus, dyslipidemia, obesity and healthy volunteer.

Interventions

None listed

Sponsors

Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine
Lead Sponsor
Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: i)Outpatients or hospitalized patients in the Yokohama City University Hospital, consenting for study paticipation. ii)staffs and medical students of the Yokohama City University, consenting for study paticipation.

Exclusion criteria

Exclusion criteria: Patinets i)who were 19 years-old or younger, ii)having corticosteroids or immunosuppressive medications within 3 month, iii)with hematological disorder, iv)with active infection, and v)that physician judged to be inappropriate.

Design outcomes

Primary

MeasureTime frame
The prevalence of non-communicating disease, including chronic kidney disease, hypertension, diabetes mellitus, and obesity.

Secondary

MeasureTime frame
The progression to the end-stage renal disease, 50% reduction in eGFR, and all-cause mortality.

Countries

Japan

Contacts

Public ContactKotaro Haruhara

Yokohama City University Graduate School of Medicine Department of Medical Science and Cardiorenal Medicine

harry@jikei.ac.jp045-787-2800

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026