The clinical study for seeking strategy how to treat rheumatoid arthritis by TNF Inhibitors

The clinical study for seeking strategy how to treat rheumatoid arthritis by TNF Inhibitors - The aggressive clinical tight control study (TACTICS trial)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016844

Enrollment

Registered

2015-03-20

Start date

2014-02-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthritis

Interventions

infliximab: standard strategy infliximab: aggressive strategy golimumab: standard strategy golimumab: aggressive strategy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Rheumatoid arthritis patients(RA) diagnosed by ACR/EULAR 2013 RA classfication criteria, and they are patients of biologics naive and inadequate response by methotrexate (MTX) therapy.

Exclusion criteria

Exclusion criteria: other csDMARDs without MTX user

Design outcomes

Primary

Measure	Time frame
Clinical remission induction rates	—

Secondary

Measure	Time frame
DAS28(ESR&CRP) SDAI CDAI HAQDI modified total sharp score	—

Countries

Japan

Contacts

Public ContactTakafumi Hagiwara

Takarazuka city hospital Rheumatology

college@katzenauge.sakura.ne.jp0797-87-1161

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026