Alzheimer'
Conditions
Interventions
Donepezil with Teprenone group 12 months
Donepezil with placebo group 12 months
Sponsors
Nanpuh Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patient who visit the Division of Neurosurgery, Nanpuh Hospital, and Alzheimer's disease is diagnosed; a administration of Donepezil is appropriate, and an agreement is given by the person or family.
Exclusion criteria
Exclusion criteria: 1) Patients with dementia except Alzheimer's disease 2) Patients with central nervous system infection 3) Normal pressure hydrocephalus merger patients 4) Patients that vitamin deficiency, electrolyte abnormality, a dysfunction thyroid are clear 5) Patients with schizophrenia 6) Patients with sensitivity to piperidine derivative containing donepezil or teprenone, Children, pregnant woman and lactating woman 7) Patients after the gallbladder extraction 8) Patients with visual disturbances, hearing impairment, and writing and literacy difficulties that affect the assessment of the neuropsychological test 9) Patients who received the drugs for Alzheimer's disease within 30 days before registration 10) Patients who received Teprenone 14 days before registration 11) Patients who are inappropriate to participate judge by attendant doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of change of ADAS-J cog score from baseline | — |
Countries
Japan
Contacts
Public ContactMasumi Nakasuji
Nanpuh Hospital Clinical Trials Support Office
Outcome results
None listed