Clinical significance of adipose tissue-derived hormones and bioactive substances: physiological differences between visceral and subcutaneous adipose tissue

Clinical significance of adipose tissue-derived hormones and bioactive substances: physiological differences between visceral and subcutaneous adipose tissue - Physiological differences between visceral and subcutaneous adipose tissues

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000016823

Enrollment

Registered

2015-03-17

Start date

2011-02-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Outpatients undergoing surgery in the following areas: general surgery, plastic surgery, and urological surgery. 2) Patients who are able to attend the hospital 3) Age: 20 years of age and older, and below 80 years old 4) Patients providing written informed consent

Exclusion criteria

Exclusion criteria: 1) Patients with severe renal and liver dysfunction 2) Patients with systemic inflammation

Design outcomes

Primary

Measure	Time frame
inflammatory mediators: IL-6, IL-10, TNF-alpha, MCP-1, leptin, adiponectin, hs-CRP, PPARgamma, Mincle, Thrombospondin 1 (THBS1/TSP-1)	—

Secondary

Measure	Time frame
body weight, waist circumference, BMI, blood pressure, HbA1c, FPG, TG, LDL-C, HDL-C, UA, BUN, Cre, visceral fat area, subcutaneous fat area	—

Countries

Japan

Contacts

Public ContactNoriko Satoh-Asahara

National Hospital Organization, Kyoto Medical Center Clinical Research Institute

nsato@kyotolan.hosp.go.jp075-641-9161

Outcome results