Efficacy of repetitive transcranial magnetic stimulation of the primary motor cortex for chemotherapy-induced neuropathic pain in patients with breast and gynecological cancer

Efficacy of repetitive transcranial magnetic stimulation of the primary motor cortex for chemotherapy-induced neuropathic pain in patients with breast and gynecological cancer - rTMS for chemotherapy-induced neuropathic pain

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016814

Enrollment

Registered

2015-03-16

Start date

2015-03-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathic pain induced by chemotherapy for breast and gynecological cancer

Interventions

Active stimulation (M1 hand) Active stimulation (M1 hand, high stimulus intensity) Active stimulation (M1 foot) Sham stimulation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with peripheral neuropathic pain induced by chemotheraphy for breast or gynecological cancer Patients with pain duration of 3 months or longer Patients with moderate or sevvere pain (VAS: 30mm or more) Patients with agreement with no change of ordinary drugs during trial Patients with an informed consent given

Exclusion criteria

Exclusion criteria: Patients suffering from cognitive impairments, aphasia, or a major psychiatric disease Patients with a desire for suicide Patients who cannot write the questionnaires Patients with an implanted metal in a head excluding a mouth Patients with a cardiac pacemaker, devices for deep brain stimulation, or an implanted medication pump Patients suffering from serious heart diseases Patients suffering from a major cerebral infarction or head a trauma Patients suffering from a brain tumor Patients with epilepsy episode history Pregnant patients

Design outcomes

Primary

Measure	Time frame
Pain reduction in visual analogue scale	—

Countries

Japan

Contacts

Public ContactKoichi Hosomi

Osaka University Department of Neuromodulation and Neurosurgery

k-hosomi@nsurg.med.osaka-u.ac.jp+81-6-6210-8435

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026