Overweight and Obesity
Conditions
Interventions
An unbalanced diet (2096kcal
Protein=13.7%, Fat=37.5%, Carbohydrate/dietary fiber ratio >
=0.04), for 2 weeks ->
Washout, for 4 weeks ->
A well-balanced diet (2096kcal
Protein=22.3%, Fat=20.8%, Carbohydrate/dietary fiber ratio <
=0.04), for 2 weeks
A well-balanced diet (2096kcal
= 0.04), for 2 weeks ->
= 0.04), for 2 weeks
Sponsors
National Hospital Organization Kyoto Medical Center
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Japanese male, Age >=20 and <=59 years 2) Body mass index >=23 kg/m2 3) Informed consent provided 4) Able to receive and cook experimental diet 5) Able to follow the instructions of the study team 6) Participated in a meal tolerance test
Exclusion criteria
Exclusion criteria: 1) Plasma glucose value >=126 mg/dL (7.0 mmol/L), LDL-cholesterol value >=180 mg/dL (4.65 mmol/L), Triglyceride value >=300 mg/dL (3.4 mmol/L), Systolic blood pressure >=160 mmHg 2) Weight change during past 1 year >=3 kg 3) Severe liver dysfunction or renal dysfunction 4) Shift worker and night-shift worker 5) Food allergy and suspected food allergy (Self-reported) 6) An unbalanced diet (not able to eat fish and meat) 7) Poor physical health such as rapid weight loss during past 2 months 8) Plan to lose weight through vigorous exercise and resistance training 9) Subjects judged by the investigator/project leader to be ineligible for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in visceral fat area | — |
Secondary
| Measure | Time frame |
|---|---|
| Change and percent change in body weight, waist circumference, hip circumference, body fat, glucose-related markers, lipid markers, oxidative stress markers, blood biochemical parameters | — |
Countries
Japan
Contacts
Public ContactNaoki Sakane
Clinical Research Institute, National Hospital Organization Kyoto Medical Center Division of Preventive Medicine
Outcome results
None listed