castration refractory prostate cancer
Conditions
Interventions
None listed
Sponsors
Working group of heavy ion therapy for genitourinary tumor, Gunma university
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Continuous PSA increase in spite of castration level of testosterone. 2) Histologically proven primary prostate adenocarcinoma 3) Gleason score is diagnosed 4) T1c-T3N0M0(2009, UICC 7th) 5) PSA value before biopsy and before this study are measured 6) No lymph node and distant metastasis 7) Age at registration is 20-80 8) Performance status is 0-2 9) Diagnosis is informed 10) Having the ability to consent
Exclusion criteria
Exclusion criteria: 1) Past radiotherapy to the pelvic region 2) Past physical treatment of the prostate (TUR-P, HIFU, etc.) 3) Past chemotherapy within 4 weeks 4) Life expectancy is less than 6 months 5) Multiple malignancies within 5 years 6) Severe comorbidity 7) Judged inappropriate for this study by physicians
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 5-yr biochemical relapse free survival | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) 5-yr overall survival 2) 5-yr cause specific survival 3) 5-yr local control 4) acute toxicity 5) late toxicity 6) QOL | — |
Countries
Japan
Contacts
Public ContactHidemasa Kawamura
Gunma University Heavy ion medical center
Outcome results
None listed