The beneficial effect of branched-chain amino acids for patients with HCV related chronic liver disease

The beneficial effect of branched-chain amino acids for patients with HCV related chronic liver disease - The beneficial effect of branched-chain amino acids for patients with HCV related chronic liver disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016750

Enrollment

100

Registered

2015-03-09

Start date

2014-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HCV related chronic liver disease

Interventions

Patients who obtained the consent, administer the BCAA enriched supplement for 12 weeks in addition to the original treatment. containing

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Age, over 20 years old 2) Male and female 3) Patients who has inslin resistance 4) Patients who has no HCC 5) Patients who obtained the consent

Exclusion criteria

Exclusion criteria: 1) Cirrotic patients with BCAA formulation while taking 2) Patients during interferon therapy in chronic hepatitis C, cirrhosis 3) Patients receiving medication for diabetes 4) Patients in the intake of dietary supplements containing the BCAA and zinc 5) Patients for branched-chain amino acids and zinc formulation, with a history of hypersensitivity 6) Pregnant woman and women who may possibly be pregnant, women in nursing

Design outcomes

Primary

Measure	Time frame
1) Improvement of insulin resistance 2) Reduction of oxidative stress	—

Secondary

Measure	Time frame
1) Change of HCV-RNA 2) Improvement of loss of zinc 3) Improvement of BTR 4) Incidence of HCC 5) Occurrence of side effect	—

Countries

Japan

Contacts

Public ContactIsao Hidaka

Yamaguchi Univercity Graduate School of Medicine Department of Gastroenterology and Hepatology

isao-h@yamaguchi-u.ac.jp0836-22-2241

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026