H. pylori infection with dyspepsia
Conditions
Interventions
Yogurt containing L. gasseri OLL2716 (90 g) was consumed once daily for 12 weeks.
placebo yogurt (identical in appearance and taste
Sponsors
Study group of LG
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria for participation were age over 30 years and confirmed H. pylori positivity.
Exclusion criteria
Exclusion criteria: included organic disorders, such as gastric cancer, gastric ulcers, duodenal ulcers, pyloric stenosis, use of NSAIDs, antibiotic treatment before the study, use of PPIs or H2 antagonists, H. pylori eradication therapy within 6 months before the study, ingestion of yogurt or lactic acid bacteria beverages, and the use of antiflatulence agents.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| he urea breath test was performed, and subjects fasted on the day of testing. Serum pepsinogen (PG) was measured and H. pylori stool antigen detection was evaluated. UBT, serum pepsinogen, and stool antigen detection were performed before and after consumption of the test product. | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastrointestinal symptoms were assessed using a visual analogue scale (VAS). Each participant kept a diary during consumption of the test product to record compliance and gastrointestinal symptoms (upper abdominal pain, bloating, indigestion, nausea, vomiting, and heartburn). | — |
Countries
Japan
Contacts
Public ContactAtsushi Takagi
Tokai University School of Medicine General Internal Medicine
Outcome results
None listed