Asthma
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Randomized controlled trials of children with chronic asthma or children with recurrent wheeze (or preschool wheezer) who use ICS longer than (or equal to) 4 weeks; we accept the definitions for children as used by the investigators in the original studies.
Exclusion criteria
Exclusion criteria: 1. Abstract only (eg, conference paper) 2. Not asthma study (eg, viral bronchiolitis) 3. Study examining dose-response relationship of ICS (because of technical difficulties in incorporating into meta-analysis) 4. Safety assessment study of ICS 5. Short term or intermittent use of ICS 6. Trials with co-intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We do not define the primary outcome in this study because no single outcome measure actually represents asthma control; instead, multiple asthma outcomes are assessed to see a more complete picture of asthma control by ICS, including pulmonary function, rescues use of medications and urgent health service use. | — |
Countries
Japan
Contacts
Graduate School of Medicine and Public Health, Kyoto University, Department of Pharmacoepidemiology