Type 2 diabetes patients with hypertriglyceridemia
Conditions
Interventions
The continued treatment with statin, and cookies meal test is performed to evaluate postprandial hypertriglyceridemia.
It'
s changed to treatment with ezetimib/fenofibrate from treatment with statin, and cookies meal test performed to evaluate postprandial hypertriglyceridemia.
Sponsors
Kagoshima University Graduate School of Medical and Dental Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: LDL <=120 mg/dl TG >=120 mg/dl HbA1c <=8.0%
Exclusion criteria
Exclusion criteria: HbA1c > 8.0%. Patients with severe liver dysfunction. Patients with history of hypersensitivity to study drugs. Serum creatinine >= 2.5 mg/dl. Patients with secondary properties and drug-induced lipid abnormalities. Patients with familial hypercholesterolemia. Pregnancy example. Patients with history of coronary artery disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We compare the lipoprotein profile and FMD(flow mediated dilation) between the two groups(Statin group and Ezetimibe/fenofibrate combination group). we compare also changes in postprandial hypertriglyceridemia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Before and after Cookies meal test, relation between lipid parameters(total cholesterol, triglycerides, HDL, LDL, LPL, apoprotein) and FMD. | — |
Countries
Japan
Contacts
Public ContactAtsushi Shinnakasu
Kagoshima University Graduate School of Medical and Dental Sciences Department of Diabetes and Endocrinology
Outcome results
None listed