Morphological and Functional Change of Coronary Perivascular Adipose Tissue in Vasospastic Angina

Morphological and Functional Change of Coronary Perivascular Adipose Tissue in Vasospastic Angina - ADIPO-VSA Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000016675

Enrollment

150

Registered

2015-03-09

Start date

2015-03-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vasospastic angina

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are suspected of vasospastic angina.

Exclusion criteria

Exclusion criteria: (1) Acute coronary syndrome (2) EF is under 40%. (3) Severe renal failure. (4) Severe contrast media allergy (5) history of cardiac surgery (6) Severe asthma (7) Diabetes which needs insulin therapy

Design outcomes

Primary

Measure	Time frame
(1)Coronary perivascular adipose tissue volume measured by cardiac CT.	—

Secondary

Measure	Time frame
(2)FDG-uptake of coronary perivascular adipose tissue measured by 18F-FDG PET. (3)FDG-uptake of vascular wall in which vasospasm occurs measured by 18F-FDG PET. (4)Vasa vasorum measured by OFDI (5)General blood examination deta, adiponectin, Rho-kinase activity (6)Metabolite measured by metabolome analysis (7)Exercise tolerance measured by cardiopulmonary exercise test (8)FDG-uptake of coronary perivascular adipose tissue measured by 18F-FDG PET at the time of follow-up.	—

Measure

Time frame

(2)FDG-uptake of coronary perivascular adipose tissue measured by 18F-FDG PET. (3)FDG-uptake of vascular wall in which vasospasm occurs measured by 18F-FDG PET. (4)Vasa vasorum measured by OFDI (5)General blood examination deta, adiponectin, Rho-kinase activity (6)Metabolite measured by metabolome analysis (7)Exercise tolerance measured by cardiopulmonary exercise test (8)FDG-uptake of coronary perivascular adipose tissue measured by 18F-FDG PET at the time of follow-up.

—

Countries

Japan

Contacts

Public ContactYasuharu Matsumoto

Tohoku University Hospital Department of Cardiovascular Medicine

matsumoto@cardio.med.tohoku.ac.jp+81-22-717-7153

Outcome results