Prognostic value of tubulointerstitial lesions, urinary N-acetyl-B-D-glucosaminidase, and urinary B2-microgrobulin in patients with type 2 diabetes and biopsy-proven diabetic nephropathy.

Prognostic value of tubulointerstitial lesions, urinary N-acetyl-B-D-glucosaminidase, and urinary B2-microgrobulin in patients with type 2 diabetes and biopsy-proven diabetic nephropathy. - Tubulointerstitial lesions and urinary biomarkers

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000016662

Enrollment

120

Registered

2015-02-27

Start date

2015-01-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic nephropathy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with type2 diabetes who underwent renal biopsy at our hospital from March 1985 to June 2011 and were confirmed to have diabetic nephropathy according to Tervaert's classification(J Am Soc Nephrol. 2010;21(4):556-63)

Exclusion criteria

Exclusion criteria: Patients in whom urinary NAG and B2-MG were not examined at the time of renal biopsy Patients whose baseline eGFR was <10 mL/min/1.73m2

Design outcomes

Primary

Measure	Time frame
A decline of eGFR by at least 50% from baseline or commencement of dialysis due to end-stage renal disease	—

Countries

Japan

Contacts

Public ContactKoki Mise

Toranomon Hospital Kajigaya Nephrology Center

kokims-frz@umin.ac.jp044-877-5111

Outcome results