A comparative randomized trial of pre-emptive dexamethasone for relief of pain after endoscopic submucosal dissection for early gastric neoplasm

A comparative randomized trial of pre-emptive dexamethasone for relief of pain after endoscopic submucosal dissection for early gastric neoplasm - A comparative randomized trial of pre-emptive dexamethasone for relief of pain after endoscopic submucosal dissection for early gastric neoplasm

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016614

Enrollment

Registered

2015-03-01

Start date

2015-02-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early gastric neoplasm

Interventions

Intravenous 0.15 mg/kg dexamethasone before ESD and placebo after ESD Placebo before ESD and intravenous 0.15 mg/kg dexamethasone after ESD

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) 20 years of age or older 2) pathologically diagnosed gastric adenoma or cancer that was eligible for ESD 3) patients who gave written informed consent from patients or responsible family members.

Exclusion criteria

Exclusion criteria: 1) patients who take pain killer within 48 hours or regularly at enrollment 2) confirmed any other disease which can induce epigastric pain such as peptic ulcer disease and gastroesophageal reflux disease 3) multiple gastric lesions for ESD 4) history of gastric surgery at enrollment 5) severe underlying disease including infection, cardiopulmonary disease, and diabetes.

Design outcomes

Primary

Measure	Time frame
Present pain intensity	—

Secondary

Measure	Time frame
Short-form McGill pain (SF-MP) categories for immediate and 6-, 12-, and 24-h postoperative periods	—

Countries

Asia(except Japan)

Contacts

Public ContactHyuk Lee

Samsung Medical Center Department of Medicine

leehyuk@skku.edu82-2-3410-3409

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026