Comparison of sugammadex and pyridostigmine for reversal of neuromuscular blockade in the absence of neuromuscular monitoring in patients undergoing laryngeal microsurgery: A single-centered retrospective study

Comparison of sugammadex and pyridostigmine for reversal of neuromuscular blockade in the absence of neuromuscular monitoring in patients undergoing laryngeal microsurgery: A single-centered retrospective study - Effectiveness of sugammadex in the absence of neuromuscular monitoring

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016602

Enrollment

100

Registered

2015-02-22

Start date

2015-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

elective laryngeal microsurgery

Interventions

sugammadex reversal group pyridostigmine reversal group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with the American Society of Anesthesiologists physical status 1 or 2, undergoing elective laryngeal microsurgery, patients who receive rocuronium for neuromuscular block and sugammadex or pyridostigmine for reversal of neuromuscular block

Exclusion criteria

Exclusion criteria: patients with renal or hepatic impairment and extremely elderly patients

Design outcomes

Primary

Measure	Time frame
anesthesia and extubation time	—

Secondary

Measure	Time frame
the total amount of rocuronium and reversal agents, the interval between the surgery end time and the administration of reversal agents, recovery time [the time to reach modified Aldrete score 10] in the postanesthesia care unit and postoperative adverse events	—

Countries

Asia(except Japan)

Contacts

Public ContactByung Gun Lim

Korea University Guro Hospital, Korea University College of Medicine Department of Anesthesiology and Pain Medicine

bglim9205@korea.ac.kr82226261437

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026