Lung cancer
Conditions
Interventions
Dynamic tumor tracking radiotherapy using Vero4DRT
Sponsors
Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) primary or metastatic lung cancer which satisfies the following conditions: Primary lung cancer (1) (a) pathological or cytological diagnosis of primary lung cancer (b) clinically diagnosed primary lung cancer with a consensus of multiple doctors based on tumor marker, CT, FDG-PET, etc. (2) tumor diameter of 5cm or less and clinical stage of IA-IB diagnosed with imaging studies Metastatic lung cancer (1) clinically diagnosed metastatic lung cancer (2) three or less tumors with diameters of 5cm or less without any extrapulmonary lesions which was diagnosed with imaging studies 2) Ineligibility to standard surgery confirmed by institutional thoracic surgeons, or patient's refusal of surgery 3) Predicted to satisfy dose constraints for the surrounding organ 4) Aged 20 years or more 5) ECOG-PS of 0 to 2 6) Able to keep the patient's position with the arms raised for 30 mins or more 7) Respiratory motion of 10 mm or more
Exclusion criteria
Exclusion criteria: 1) history of radiotherapy to the same area 2) active interstitial pneumonia or pulmonary fibrosis 3) severe diabetes mellitus or collagen disease 4) female who are pregnant or in lactation 5) metal disease which prevents registration of the study 6) other issues which are considered to be inappropriate for the study by the doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2-year local control rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival, progression-free survival, local progression-free survival, adverse event, severe adverse event, accuracy in the treatment, dose-volume metrics | — |
Countries
Japan
Contacts
Public ContactYukinori Matsuo
Kyoto University Dept of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine
Outcome results
None listed