laparoscopic total hysterectomy patients under general anesthesia
Conditions
Interventions
1.Fentanyl 1000gm in total volume 100mL PCA to be administered over the first 48 h postoperatively
Fentanyl 500gm + Nefopam (NFP) 200 mg in total volume 100mL PCA to be administered over the first
Sponsors
Korea University Guro Hospital, Department of Anesthesiology and Pain medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1)American Society of Anesthesiologists (ASA) physical status class I, II 2) patients were scheduled for laparoscopic total hysterectomy under general anesthesia
Exclusion criteria
Exclusion criteria: 1)ASA physical status class III, IV 2)BMI> 35 3)history of drug abuse or suspected drug abuse 4)history of illegal drug use or drug dependence 5)history of chronic pain disease 6)known intolerance of or hypersensitivity to nefopam 7)those who have or had conditions with a possible risk of affecting the interpretation of the study results, safety, and subject participation including cancer, neurologic, psychologic, cardiac, hepatic, hematologic, muscular, dermatologic, genital problems, or were in an immunocompromised state 8) others who the investigator judged to be inappropriate candidates for participation in the clinical study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total fentanyl consumption during 48h | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.relief of VPS(verbal pain score) and NRS (numerical rating scale) score 2.incidence of side effect | — |
Countries
Asia(except Japan)
Contacts
Public ContactJung eun Kim
Korea University Guro Hospital Department of Anesthesiology and Pain medicine
Outcome results
None listed