hyperhidrosis
Conditions
Interventions
The bilateral lesions are chosen as the treatment areas. Rapamycin gel is applied on the left lesion, and the gel base is applied on the right lesion. Amount of sweating is measured before applicat
Sponsors
Department of Dermatology Graduate School of Medicine, Osaka University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Healthy volunteers over 20 years of age. 2) Healthy volunteers who can give written consent by themselves in understanding after having received enough explanation on this examination.
Exclusion criteria
Exclusion criteria: 1) A person who cannot carry out this treatment plan. 2) A person who have allergy to macrolide antibiotics. 3) A person who received oral administration of rapamycin or RAD001 within 12 months prior to the study entry. 4) A person who received topical administration of rapamycin or RAD001 within three days prior to the study entry. 5) A person who received topical treatment of aluminum chloride or iontophoresis within one months prior to the study entry. 6) A person who received local injection of Botox within three months prior to the study entry. 7) A person who received sympathectomy within 12 months prior to the study entry. 8) A person during pregnancy or lactation 9) A person who cannot undergo QSART and starch-iodine test 10) A person who were judged unsuitable for this study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin findings at the site of topical application Subjective findings at the site of topical application Serious adverse events Amount of sweating | — |
Countries
Japan
Contacts
Public ContactMari Wataya-Kaneda
Graduate School of Medicine, Osaka University Department of Dermatology
Outcome results
None listed