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A study on serum diamine oxidase activity and pathological analysis of duodenal mucositis in patients receiving chemotherapy

A study on serum diamine oxidase activity and pathological analysis of duodenal mucositis in patients receiving chemotherapy - A study of small bowel mucosal damage by serum DAO activity and duodenal mucosa histopathology

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000016478
Enrollment
6
Registered
2015-02-09
Start date
2015-02-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unresectable metastatic gastric cancer who received docetaxel, cisplatin and S-1 combination chemotherapy (DCS chemotherapy)

Interventions

After inserting the oral endoscope, histological examination of the duodenal mucosa

Sponsors

University of Tokushima Hospital Gastroenterological medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Age: 13 to 79 years old Gender: Not specified Inpatient/outpatient: Not specified

Exclusion criteria

Exclusion criteria: 1)Patients with acute abdomen 2)Patients with severe acute inflammation 3)Patients in a very bad general condition 4)Patients with suspected intestinal perforation 5)Patients having severe blood clotting defect 6)Patients with severe hepatic function 7)Patients with severe respiratory diseases or circulatory diseases 8)Gravia and possibly pregnant patients 9)Patients who do not have the capacity or intention to cooperate with the trial procedures 10)Patients, the investigator(or the subinvestigator) considers, inappropriate for entry into the trial 11)Sick or injured persons in life-threatening conditions and from whom consent for their participation in the trial

Design outcomes

Primary

MeasureTime frame
Serum diamine oxidase and duodenal histopathology (villous atrophy)

Countries

Japan

Contacts

Public ContactJinsei Miyoshi

Health Biosciences, The University of Tokushima Graduate school Gastroenterology and Oncology

jinsei03442000@gmail.com088-633-7122

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026