The effects of propofol on the cardiac conduction system and the cardiac autonomic nervous system

The effects of propofol on the cardiac conduction system and the cardiac autonomic nervous system - The effects of propofol on the cardiac conduction system and the cardiac autonomic nervous system

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016448

Enrollment

Registered

2015-02-05

Start date

2014-09-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric patients undergoing an electrophysiologic study and the radiofrequency catheter ablation

Interventions

After continuous propofol infusion at a rate of 5mg/kg/h,2mg/kg of propofol is injected,followed by continuous infusion of propofol at a rate of 10mg/kg/h for 10min

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA physical status 1 and 2 pediatric patients who were scheduled undergoing electrophysiologic study and radiofrequency catheter ablation for tachyarrhythmia

Exclusion criteria

Exclusion criteria: Patients with allergy to propofol and its solvents Patients with severe heart diseases Patients with liver dysfunction Patients with renal dysfunction

Design outcomes

Primary

Measure	Time frame
sinus node recovery time sinoatrial conduction time atrial-His intervals His-ventricular intervals heart rate valiability analysis	—

Countries

Japan

Contacts

Public ContactMayuka Matsushima

Kinki University Faculty of Medicine Deparment of Anesthesiology

m-shiba@med.kindai.ac.jp072-366-0221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026