Overweight and Obesity
Conditions
Interventions
An unbalanced diet (636kcal
Protein=14.2%, Fat=34.4%, Carbohydrate/dietary fiber ratio >
=0.04), a meal tolerance test. ->
A well-balanced diet (661kcal
Protein=20.5%, Fat=22.6%, Carbohydrate/dietary fiber ratio <
=0.04), a meal tolerance test.
A well-balanced diet (661kcal
= 0.04), a meal tolerance test. ->
= 0.04), a meal tolerance test.
Sponsors
National Hospital Organization Kyoto Medical Center
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Japanese male, Age >=20 and <=59 years 2) Body mass index >=23 kg/m2 3) Informed consent provided 4) Able to receive and cook experimental diet 5) Able to follow the instructions of the study team
Exclusion criteria
Exclusion criteria: 1) Plasma glucose value >=126 mg/dL (7.0 mmol/L), LDL-cholesterol value >=180 mg/dL (4.65 mmol/L), Triglyceride value >=300 mg/dL (3.4 mmol/L), Systolic blood pressure >=160 mmHg 2) Weight change during past 1 year >=3 kg 3) Severe liver dysfunction or renal dysfunction 4) Shift worker and night-shift worker 5) Food allergy and suspected food allergy (Self-reported) 6) An unbalanced diet (not able to eat fish and meat) 7) Poor physical health such as rapid weight loss during past 2 months 8) Plan to lose weight through vigorous exercise and resistance training 9) Subjects judged by the investigator/project leader to be ineligible for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut hormones (Over 4 hours after eating) | — |
Secondary
| Measure | Time frame |
|---|---|
| Change and percent change in glucose-related markers, lipid markers, oxidative stress markers, experimental diet load test. (Over 4 hours after eating) | — |
Countries
Japan
Contacts
Public ContactNaoki Sakane
Clinical Research Institute, National Hospital Organization Kyoto Medical Center Division of Preventive Medicine
Outcome results
None listed