Amelioration of glucose homeostasis and visceral adiposity in obese type 2 diabetes by mild electrical stimulation with heat shock (MES+HS) therapy

Amelioration of glucose homeostasis and visceral adiposity in obese type 2 diabetes by mild electrical stimulation with heat shock (MES+HS) therapy - Clinical effects of MES+HS in diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016309

Enrollment

Registered

2015-01-23

Start date

2014-03-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obese type 2 diabetes mellitus

Interventions

MES+HS treatment twice a week without DPP-4 inhibitor for 12 weeks MES+HS treatment 4 times a week without DPP-4 inhibitor for 12 weeks MES+HS treatment 7 times a week without DPP-4 inhibitor for 12 w

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Waist circumference: Male: more than 85 cm Female: more than 90 cm 2) HbA1c (NGSP): from 7.0% to less than 9.4% 3) Treated with or without DPP-4 inhibitors

Exclusion criteria

Exclusion criteria: i) Past history or current medication of myocardial infarction, angina, apoplexy and arteriosclerosis obliterans. ii)Severe wound, infections, pre- or post-operation. iii)Severe liver dysfunction (GOT and/or GPT: greater than 100U). iv)Chronic heart failure, familial dyslipidemia. v)Severe diabetic complications. vi)Pacemaker carrier.

Design outcomes

Primary

Measure	Time frame
1) Visceral adipose volume 2) HbA1c	—

Secondary

Measure	Time frame
1) chronic inflammatory markers 2) hepatic steatosis marker 3) renal function 4) lipid metabolism	—

Countries

Japan

Contacts

Public ContactTatsuya Kondo

Faculty of Life Sciences, Kumamoto University Department of Metabolic Medicine

t-kondo@gpo.kumamoto-u.ac.jp096-373-5169

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026