Non-interventional retrospective observation study for pretretment prediction of rheumatoid arthritis patients' response to anti-cytokine therapy using serum cytokine / chemkine / soluble receptor biomarkers

Non-interventional retrospective observation study for pretretment prediction of rheumatoid arthritis patients' response to anti-cytokine therapy using serum cytokine / chemkine / soluble receptor biomarkers - Retrospective observation study for prediction of response in RA before anti-cytokine therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000016298

Enrollment

150

Registered

2015-01-21

Start date

2009-09-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthritis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Rheumatoid arthritis (RA) who failed prior methotrexate treatment. They are treated with Tocilizumab or Etanercept over 16 weeks

Exclusion criteria

Exclusion criteria: RA patients treated with Tocilizumab or Etanercept within 16 weeks

Design outcomes

Primary

Measure	Time frame
A patient can select an effective therapeutic reagent indivisually	—

Secondary

Measure	Time frame
A patient predicts the clinical response before therapy using pretreatment biomarkes in serum	—

Countries

Japan

Contacts

Public ContactKazuyuki Yoshizaki

Osaka University Graduate School of Engineering

kyoshi@chem.eng.osaka-u.ac.jp06-6872-7460

Outcome results