effectiveness of prophylaxis of post-ercp pancreatitis by a rectal diclofenac and sublingual nitrate.-randomized controlled multicenter trial-

effectiveness of prophylaxis of post-ercp pancreatitis by a rectal diclofenac and sublingual nitrate.-randomized controlled multicenter trial- - a randomized trial of rectal diclofenac and sublingual nitrate for prevention of post ercp pancreatitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016274

Enrollment

900

Registered

2015-02-05

Start date

2015-03-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-ERCP pancretitis

Interventions

patients received a 5mg of sublingual nitrate before ERCP and received a suppository containing 50mg of diclofenac after ERCP. patients received a suppository containing 50mg of diclofenac after ERC

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are planned ERCP

Exclusion criteria

Exclusion criteria: 1)Patients with performance status 4. 2)Age<20 3)Body weight<50Kg 4)Patients who cannot access to Vater,s papilla. 5)Patients with a history of EST and EPBD. 6)Patients with acute pancreatitis 7)Patients with chronic pancreatitis 8)Patients with pancreatic head tumor 9)Patients who performed operation of reconstraction for intestinal track by gastrectomy. 10) Patients who had a contraindication to the use of NSAIDs and nitrate. 11) Patients who were already taking nitrates. 12)Patietns without informed concent. 13)Patients who are judged inappropriate by chief medical examiner.

Design outcomes

Primary

Measure	Time frame
Incidence rate of post-ERCP pancreatitis	—

Countries

Japan

Contacts

Public ContactTakeshi Tomoda

Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Department of Gastroenterology & Hepatology

tomotake79@yahoo.co.jp086-235-7219

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026