The effect of carnitine for intermittent claudication of peripheral arterial disease patient with sarcopenia and carnitine deficiency

The effect of carnitine for intermittent claudication of peripheral arterial disease patient with sarcopenia and carnitine deficiency - The effect of carnitine for intermittent claudication of peripheral arterial disease patient with sarcopenia and carnitine deficiency

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016267

Enrollment

Registered

2015-01-26

Start date

2015-01-26

Completion date

Unknown

Last updated

2025-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral arterial disease(PAD), Arteriosclerosis obliterans(ASO)

Interventions

carnitine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria:

Exclusion criteria

Exclusion criteria: 1) Acute limb ischemia 2) Preferred revascularization for symptoms 3) Comorbidity taking precedence of treatment 4) Bleeding disorders 5) Congestive heart failure 6) Drug allergy of cilostazole or carnitine 7) Pregnant female 8) The patient judged inappropriate by the doctor

Design outcomes

Primary

Measure	Time frame
Pretreatment of carnitine: cross-sectional areas of skeletal muscle at the thigh and lumbar part, serum carnitine level, absolute claudication distance, symptom, ABI Post treatment of carnitine: serum carnitine level, absolute claudication distance, symptom, cross-sectional areas of skeletal muscle at the thigh and lumbar part at 6 months after carnitine treatment	—

Secondary

Measure	Time frame
Adverse event, serum carnitine level, absolute claudication distance, symptom at 4 weeks and 3 months after carnitine treatment	—

Countries

Japan

Contacts

Public ContactTakuya Matsumoto

Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Department of Surgery and Science

takum@surg2.med.kyushu-u.ac.jp092-642-5466

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Feb 4, 2026