Depressor and anti-inflammatory effects of angiotensin II receptor blockers in metabolic and/or hypertensive patients with coronary artery disease

Depressor and anti-inflammatory effects of angiotensin II receptor blockers in metabolic and/or hypertensive patients with coronary artery disease - DIAMOND study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016247

Enrollment

Registered

2015-01-17

Start date

2013-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

The patients with hypertension who received ARBs except for azilsartan and olmesartan are enrolled. The patients are randomly divided into two groups (azilsartan and olmesartan groups) and treated for

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients with hypertension who receive ARBs expect for azilsartan and olmesartan 2.Age is 20 years old or more. 3.Patients who undergo CAG 4.Patients who give their informed consent to participate for the present study.

Exclusion criteria

Exclusion criteria: 1.Severe liver dysfunction. 2.Severe renal dysfunction. 3.Pregnancy or lactation in women. 4.Patients with a history of allergy to any component of the study medications. 5.Patients corresponding to the contraindication of study medications. 6.Ineligible patients according to the judgment by physician.

Design outcomes

Primary

Measure	Time frame
Depressor effects and the percentage of patients who reach the target blood pressure.	—

Secondary

Measure	Time frame
1.Anti-inflammatory effects 2.Rate of in-stent restenosis	—

Countries

Japan

Contacts

Public ContactShin-ichiro Miura

Fukuoka University School of Medicine Department of Cardiology

miuras@cis.fukuoka-u.ac.jp81-92-801-1011

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026