The dose fluctuation effect of glucocorticoid on the quality of life (QOL) and metabolism in patients with secondary adrenal insufficiency

The dose fluctuation effect of glucocorticoid on the quality of life (QOL) and metabolism in patients with secondary adrenal insufficiency - The dose fluctuation effect of glucocorticoid on the quality of life (QOL) and metabolism in patients with secondary adrenal insufficiency

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016219

Enrollment

Registered

2015-01-15

Start date

2014-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Secondary adrenal insufficiency

Interventions

Duration 1 month Subject secondary adrenal insufficiency glucocorticoid treatment hydrocortisone 10 mg/day Duration 1 month Subject secondary adrenal insufficiency glucocorticoid treatment hyd

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The secondary adrenal insufficiency patient who needs glucocorticoid treatment

Exclusion criteria

Exclusion criteria: Patient who has severe heart failure (NYHA grade 3 or more) Patient whose serum bilirubin is more than 2.0 mg/dL Patient whose serum AST or ALT concentration is more than 100 IU/mL Patient who has malignancy Patient who has received glucocoriticoids therapy for another diseases Patient who is unsuitable for this study (Judged by a doctor)

Design outcomes

Primary

Measure	Time frame
QOL, Blood pressure, glucose metabolism, lipid metabolism, bone metabolism	—

Countries

Japan

Contacts

Public ContactMichio Otsuki

Osaka University Graduate School of Medicine Department of Metabolic Medicine

otsuki@endmet.med.osaka-u.ac.jp06-6879-3732

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026