Fuchs corneal endothelial dystrophy
Conditions
Interventions
Removal of Descemet membrane
Sponsors
Tokyo University Hospital
Department of Ophthalmology, Tokyo University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed as Fuchs corneal endothelial dystrophy 2) Corneal opacity and edema limited to corneal central area 3) Less than 500mm2 or uncountable corneal endothelial density 4) Corrected visual acuity is equal to or less than 16/20 5) Intra-ocular pressure is equal to or 21mmHg
Exclusion criteria
Exclusion criteria: 1) Inappropriate patient based on screening tests 2) Uncontrolable dry eye 3) Corneas or conjunctivae with active bacterial, fungal or virus infection 4) Corneas with corneal epithelial or stromal diseases 5) Glaucomatous eyes treated with anti-glaucoma eye drops 6) Eyes with cataract affecting visual acuity 7) Patients within 1 month after cataract surgery 8) Eyes with macular disease 9) Patients with hypersensitivity to antibiotics and corticosteroid hormone 10) Patients with expecting mother or possible pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Corrected visual acuity | — |
Secondary
| Measure | Time frame |
|---|---|
| corneal thickness, corneal endothelial cell density, intraocular pressure, corneal stromal opacity | — |
Countries
Japan
Contacts
Public ContactSatoru Yamagami
Tokyo University Hospital Corneal transplantation section
Outcome results
None listed