Investigation for the effect of duloxetine on adolescent depression; Ver. 2

Investigation for the effect of duloxetine on adolescent depression; Ver. 2 - E-DAD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016192

Enrollment

100

Registered

2015-03-01

Start date

2015-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depressive Disorder

Interventions

* On

y cognitive behavioral therapy of 50 minutes. * 1W, 4W, 6W, 8W total 4 times. * Cognitive behavioral therapy of 50 min. and duloxetine. * CBT

1W, 4W, 6W, 8W total 4 times. * Duloxetine

At first we will prescribe 20mg. 1 week later we will increase to 40mg. 3 week later, depending on the request of subjects, we will regulate quantity of prescription from 20mg to 60mg. We will not cha

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients of Major Depressive Disorder diagnosed by both of DSM-IV-TR and DSM-5.

Exclusion criteria

Exclusion criteria: * Remitted or partial remitted patients * Patients with sever inhibition so as not to tolerate CBT, questionnaire and structured interview * Pregnant women * Patients with physical disorder

Design outcomes

Primary

Measure	Time frame
Quolity of Life; SF-36v2	—

Secondary

Measure	Time frame
Depression; BDI-II Anxiety; STAI Autistic Tnedency; PARS-TR Attention Deficit and/or Hyperactivity; ADHD-RS	—

Countries

Japan

Contacts

Public ContactTakahiko Inagaki

Shiga University of Medical Science Department of Community Psychiatric Medicine

kerosuke@belle.shiga-med.ac.jp077-548-2291

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026