A treatment option for substance dependence
Conditions
Interventions
Anodal stimulation of the left DLPFC: The anode place at the left DLPFC and cathode placed at the right DLPFC, stimulated by tDCS. A constant current of 2mA intensity, provided by battery, was applie
Sponsors
Taipei Veterans General Hospital, Taiwan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Meet the Structured Clinical Interview for DSM-IV(SCID)criteria for Zolpidem/Nicotine dependence, and the duration over one year (2) Evaluate the comorbidity by MINI interview
Exclusion criteria
Exclusion criteria: the ones who suffer from the severe medical (i.e.: arrhythmia) or brain-injury disease (i.e.: histories ofneurostimulator implantation stroke, epilepsy, brain tumor, brain infection, brain hemorrhage, brain pressure elevation); pregnant woman; neuro-device implantation; Pacemaker; Surgical intervention of brain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BZD dependence self report questionnaire for craving of Zolpidem; Fagerstrom Test for Nicotine Dependence (FTND) for Nicotine dependence; Visual analogue scale (VAS);Depression and somatic symptoms scale (DSSS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Nerocognitive testings will be also performed three times, baseline, Day 5 and 2 weeks post-treatment Go/no-go back; CANTAB | — |
Countries
Asia(except Japan)
Contacts
Public ContactCheng-Ta Li
Taipei Veterans General Hospital, Taiwan Psychiatry
Outcome results
None listed