Influence of cytochrome P450 phenotypes on changes of drug-induced these enzyme activities

Influence of cytochrome P450 phenotypes on changes of drug-induced these enzyme activities - Influence of cytochrome P450 phenotypes on changes of drug-induced these enzyme activities

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000016113

Enrollment

Registered

2015-01-06

Start date

2013-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteer

Interventions

Drugs (CYP inhibitor and inducer)

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy adult males (older than age 20 years old)

Exclusion criteria

Exclusion criteria: (1) Liver dysfunction (2) Renal dysfunction (3) Inability to obtain informed consent (4) Participant with diseases under treatment (5) Drug allergy (6) drug dependence or alcohol dependence (7) Inappropriate participants due to other reasons

Design outcomes

Primary

Measure	Time frame
Cytochrome P450 1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A activities	—

Countries

Japan

Contacts

Public ContactKeiichi Odagiri

Hamamatsu University School of Medicine Department of Clinical Pharmacology & Therapeutics

kodagiri@hama-med.ac.jp053-435-2385

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026