Research on a Quantitative Assessment of Skin Symptoms Caused by Chemotherapy Using Molecular Target Drugs

Research on a Quantitative Assessment of Skin Symptoms Caused by Chemotherapy Using Molecular Target Drugs - Quantitative Assessment of Skin Symptoms Caused by Chemotherapy Using Molecular Target Drugs

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000015857

Enrollment

Registered

2014-12-05

Start date

2014-12-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small-cell lung cancer and colorectal cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Non-small-cell lung cancer patients who are treated with afatinib (giotrif) or erlotinib (tarceva) and colorectal cancer patients who are treated with cetuximab (erbitax). 2) PS is from 0 to 1. 3) Patients who agreed to participate in this study.

Exclusion criteria

Exclusion criteria: 1) Patients who have skin symptoms that influence skin functions such as atopic dermatitis. 2) Patients who receive treatments that influence skin functions such as steroids and antibacterial drugs. 3) Patients who are unable to control dependence. 4) Patients who are unable to respond to self-completed questionnaires. 5) Physicians decide it is inappropriate for the patients to participate in this study.

Design outcomes

Primary

Measure	Time frame
<Assessment by devices> 1) Transepidermal water loss 2) Capacitance (stratum corneum-epidermal water) 3) Erythema & melanin index 4) Visia (Facial skin condition) <Visual assessment> NCI-CTC (ver. 4.0 Japanese version JCOG) <Self-completed questionnaires> Skindex 29 (QOL regarding skin symptoms)	—

Countries

Japan

Contacts

Public ContactKeiko Nozawa

National Cancer Center Hospital Appearance Support Center

knozawa@ncc.go.jp03-3547-5201(3015)

Outcome results